The core conserved molecular identities of neuronal and non-neuronal cell types allow us to generate a cross-species consensus classification of cell types, and to infer conserved properties of cell types across species. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monkeys and mice, we demonstrate a broadly conserved cellular makeup of this region, with similarities that mirror evolutionary distance and are consistent between the transcriptome and epigenome. The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals 1. Nature volume 598, pages 111–119 ( 2021) Cite this article
Comparative cellular analysis of motor cortex in human, marmoset and mouse
0 kommentar(er)
